Johan Garssen Selected Research

Toll-Like Receptors (Toll-Like Receptor)

4/2024	Effects of toll-like receptor agonists and SARS-CoV-2 antigens on interferon (IFN) expression by peripheral blood CD3+ T cells from COVID-19 patients.
11/2019	Oligosaccharides Modulate Rotavirus-Associated Dysbiosis and TLR Gene Expression in Neonatal Rats.
1/2018	Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice.
12/2017	Transcriptional modulation of pattern recognition receptors in chronic colitis in mice is accompanied with Th1 and Th17 response.
8/2017	Pattern recognitions receptors in immunodeficiency disorders.
1/2014	Toll-like receptor (TLR)-1/2 triggering of multiple myeloma cells modulates their adhesion to bone marrow stromal cells and enhances bortezomib-induced apoptosis.
12/2013	Transcriptional modulation of pattern recognition receptors in acute colitis in mice.
1/2013	Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
1/2013	Differential regulation of inflammation and immunity in mild and severe experimental asthma.
4/2012	Dual role of Toll-like receptors in asthma and chronic obstructive pulmonary disease.

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Johan Garssen Research Topics

Disease

53	Hypersensitivity (Allergy) 01/2023 - 09/2002
48	Inflammation (Inflammations) 01/2024 - 02/2006
30	Food Hypersensitivity (Food Allergy) 11/2023 - 05/2004
27	Milk Hypersensitivity (Milk Allergy) 05/2023 - 05/2004
25	Infections 04/2023 - 08/2002
19	Asthma (Bronchial Asthma) 06/2022 - 09/2011
18	Neoplasms (Cancer) 03/2022 - 11/2011
14	Chronic Obstructive Pulmonary Disease (COPD) 04/2024 - 10/2011
10	Anaphylaxis (Anaphylactic Shock) 07/2022 - 08/2007
10	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020 - 05/2008
9	Human Influenza (Influenza) 09/2021 - 08/2006
8	Diarrhea 04/2023 - 03/2011
8	Multiple Myeloma 05/2022 - 11/2011
7	Autism Spectrum Disorder 04/2024 - 01/2017
7	Arthritis (Polyarthritis) 01/2019 - 02/2006
7	Colitis 01/2018 - 01/2013
6	Tuberculosis (Tuberculoses) 01/2019 - 01/2017
5	COVID-19 04/2024 - 01/2020
5	Parkinson Disease (Parkinson's Disease) 01/2024 - 12/2017
5	Peanut Hypersensitivity (Peanut Allergy) 04/2019 - 01/2017
5	Sarcoidosis (Schaumann Disease) 01/2018 - 01/2015
5	Porcine Reproductive and Respiratory Syndrome (PRRS) 12/2017 - 01/2013
5	Hepatitis B 01/2004 - 05/2002
4	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 09/2002
4	Leukemia 10/2018 - 11/2008
4	Lung Diseases (Lung Disease) 11/2016 - 10/2011
4	Atopic Dermatitis (Atopic Eczema) 08/2013 - 06/2010
3	Neuroinflammatory Diseases 04/2024 - 01/2019
3	Rotavirus Infections 04/2023 - 03/2011
3	Body Weight (Weight, Body) 01/2022 - 07/2015
3	Respiratory Hypersensitivity 01/2021 - 11/2016
3	Chronic Disease (Chronic Diseases) 01/2021 - 01/2013
3	Lung Neoplasms (Lung Cancer) 01/2018 - 05/2015
3	Atherosclerosis 01/2018 - 07/2011
3	Communicable Diseases (Infectious Diseases) 10/2016 - 09/2002
3	Eosinophilia 04/2015 - 11/2012
3	Contact Dermatitis (Eczema, Contact) 09/2004 - 10/2003
2	Obesity 04/2024 - 10/2021

Drug/Important Bio-Agent (IBA)

36	OligosaccharidesIBA 03/2022 - 08/2006
30	CytokinesIBA 07/2022 - 03/2003
24	Immunoglobulin E (IgE)IBA 01/2023 - 07/2002
19	AllergensIBA 11/2023 - 01/2008
19	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2016
19	Proteins (Proteins, Gene)FDA Link 08/2023 - 05/2008
16	PrebioticsIBA 04/2024 - 10/2005
12	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2024 - 05/2008
12	AntigensIBA 04/2024 - 05/2004
11	SmokeIBA 04/2024 - 02/2011
11	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 05/2022 - 01/2012
10	OvalbuminIBA 10/2022 - 10/2005
10	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 07/2002
10	VaccinesIBA 03/2021 - 08/2002
9	MicroRNAs (MicroRNA)IBA 07/2020 - 01/2016
9	Pattern Recognition ReceptorsIBA 01/2018 - 01/2013
8	Peptides (Polypeptides)IBA 05/2023 - 11/2013
8	LipopolysaccharidesIBA 05/2023 - 02/2006
7	Messenger RNA (mRNA)IBA 04/2024 - 01/2013
7	Lactoglobulins (beta-Lactoglobulin)FDA Link 05/2023 - 11/2013
7	Amino Acids FDA Link 01/2022 - 01/2018
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 09/2011
7	CollagenIBA 04/2014 - 02/2011
6	Whey ProteinsIBA 07/2021 - 01/2016
6	AntibodiesIBA 01/2019 - 05/2002
6	Glycine (Aminoacetic Acid)FDA LinkGeneric 10/2018 - 12/2007
6	ZymosanIBA 01/2018 - 02/2006
6	Dextrans (Dextran)FDA Link 12/2017 - 01/2013
6	Immunoglobulin G (IgG)IBA 10/2013 - 05/2002
5	2'-fucosyllactoseIBA 04/2023 - 01/2018
5	ChemokinesIBA 08/2022 - 05/2008
5	Bortezomib (Velcade)FDA Link 05/2022 - 01/2014
5	deoxynivalenolIBA 09/2021 - 06/2015
5	PectinsIBA 01/2020 - 06/2007
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 12/2017 - 01/2013
4	Antiviral Agents (Antivirals)IBA 04/2023 - 07/2012
4	Eicosapentaenoic AcidIBA 05/2022 - 02/2018
4	LigandsIBA 04/2019 - 01/2014
4	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019 - 01/2017
4	Interleukin-10 (Interleukin 10)IBA 01/2018 - 05/2004
4	Budesonide (Pulmicort)FDA LinkGeneric 01/2018 - 04/2014
4	Proline (L-Proline)FDA Link 04/2014 - 10/2011
3	Interleukin-8 (Interleukin 8)IBA 08/2022 - 01/2015
3	Docosahexaenoic AcidsIBA 05/2022 - 02/2018
3	EndotoxinsIBA 01/2022 - 01/2019
3	Interleukin-13IBA 01/2022 - 11/2012
3	Volatile Fatty AcidsIBA 11/2021 - 01/2017
3	Fatty Acids (Saturated Fatty Acids)IBA 10/2021 - 04/2011
3	Glutamic Acid (Glutamate)FDA Link 06/2021 - 04/2014
3	Interleukin-6 (Interleukin 6)IBA 11/2019 - 11/2011
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2019 - 01/2017
3	RNA (Ribonucleic Acid)IBA 06/2018 - 12/2016
3	Interleukin-17 (Interleukin 17)IBA 01/2017 - 12/2013
3	Transcription Factors (Transcription Factor)IBA 04/2014 - 01/2013
3	Caseins (Casein)FDA Link 03/2013 - 01/2008
2	Toll-Like Receptor AgonistsIBA 04/2024 - 08/2017
2	InterferonsIBA 04/2024 - 04/2019
2	Butyrates (Butyrate)IBA 01/2024 - 01/2019

Therapy/Procedure

17	Therapeutics 02/2023 - 05/2008
10	Immunotherapy 01/2020 - 11/2013
6	Drug Therapy (Chemotherapy) 03/2022 - 07/2011
3	Immunomodulation 03/2021 - 09/2002